Aerobic capacity and disease activity in children, adolescents and young adults with juvenile idiopathic arthritis (JIA)

نویسندگان

  • Philomien A van Pelt
  • Tim Takken
  • Marco van Brussel
  • Inge de Witte
  • Aike A Kruize
  • Nico M Wulffraat
چکیده

UNLABELLED BACKGROUND As patients with juvenile idiopathic arthritis (JIA) progress into adulthood, long-term outcome is determined by disease activity, physical and psychosocial development. Decreased aerobic capacity may play a critical role in health-related outcomes in JIA, since it has been linked with cardiovascular morbidity and mortality in late adulthood. The objectives of the current study are to examine the aerobic capacity and its relation to parameters of disease activity in children, adolescents and young adults with JIA. METHODS Sixty-three patients with JIA (aged 10-27 years) were cross sectional studied regarding their aerobic capacity and correlations were made to demographic, disease-related variables, and medication utilization. in a cross-sectional study group of 63 patients of all subtypes. Patients were divided in three age groups, 10-13 years; 14-17 years and 18-27 years. RESULTS Reduced aerobic capacity is found in clinical remission as well as active disease in all subtypes and all age groups. Aerobic capacity is more impaired in active disease shown by DAS 28, JADAS 27, ESR and serum thrombocyte counts. Lower haemoglobin has a negative impact. Long-term used medication including methotrexate and corticosteroids didn't influence outcome. There is no association with current sports participation. CONCLUSION Reduced aerobic capacity is present in children and adolescents with JIA, both in active disease and in patients with remission. Measures of aerobic capacity may serve as important outcome measure in JIA.

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Notice of redundant publication: Aerobic capacity and disease activity in children, adolescents and young adults with juvenile idiopathic arthritis (JIA)

Aerobic capacity and disease activity in children, adolescents and young adults with juvenile idiopathic arthritis (JIA). The Editors-in-Chief would like to alert readers that due to an error during the publication process this article [1] was published twice. The original article can be found in this journal [2]. References 1. Pelt PA, et al: Aerobic capacity and disease activity in children, ...

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عنوان ژورنال:

دوره 10  شماره 

صفحات  -

تاریخ انتشار 2012